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Karo Sedighiani is an Assistant Professor in the Mechanics of Materials group of the Department of Mechanical Engineering at Eindhoven University of Technology (ºÚÁϸ£ÀûÍø). He studies the mechanical behavior of metallic materials, with a particular focus on steels in the context of sustainable and circular steel production and processing. 
His research is rooted in computational mechanical metallurgy, combining crystal plasticity, micromechanics, and multiscale modeling to account for microstructural state and its evolution under deformation. Within this framework, he investigates how microstructural evolution governs mechanical response, including anisotropy and damage evolution, across length scales from individual grains to component-level performance. He further investigates deformation-driven microstructural state evolution as physics-based input for models of thermomechanical processing and related metallurgical phenomena, such as recrystallization. An overarching objective of his research is to enable predictive, physics-based digital modeling frameworks that connect processing-induced microstructural state to material performance. 
In parallel to his academic appointment, he is a Principal Researcher at Tata Steel Nederland R&D, where he is involved in multiple industrial–academic research programs on microstructure-based and scale-bridging modeling frameworks for next-generation steels.

Understanding how microstructural evolution governs the mechanical behavior of metals is key to developing physics-based predictive tools for next-generation circular and green steel processing.

Karo obtained his PhD in Materials Science and Engineering from Delft University of Technology, in collaboration with the Max-Planck-Institut for Sustainable Materials in Düsseldorf. His doctoral research focused on crystal plasticity simulations of in-grain microstructural evolution during large plastic deformation, under the supervision of Martin Diehl, Dierk Raabe, Franz Roters, and Jilt Sietsma. He obtained his MSc in Mechanical Engineering from Eindhoven University of Technology. Alongside his academic career, he has held research-oriented industrial positions at Medtronic (2013–2017) and Tata Steel Nederland (since 2022), working on microstructure-sensitive modeling, computational mechanics, and durability of advanced material systems. Since 2025, he holds a part-time appointment as Assistant Professor at Eindhoven University of Technology (ºÚÁϸ£ÀûÍø), alongside his research position at Tata Steel Nederland.