黑料福利网

The National Institute for Health and Care Excellence recommends that all patients should be monitored to help identify those whose clinical condition is deteriorating or is at risk of deterioration. Adverse events are estimated to affect up to 12% of hospitalized patients and to cause up to 95,000 patient deaths per year in the European Union alone Early Warning Systems capture deterioration detection using physiological vital signs (blood pressure, respiration rate, etc). To obtain a clinical relevant scoring methodology to quantify the severity of these phenomena, two issues have to be resolved: (1) have a technology available that simultaneously can measure relevant factors in semi-continuous manner and (2) provide signal analysis and data analytics to discover clinically relevant relationships between the measured parameters and the above mentioned health indicators. The Sentinel project will resolve these issues by developing technologies resulting in a wearable solution that integrates semi-continuous quantitative hybrid sensing of physiological, contextual, and biomolecule markers, including affiliated algorithms, manufacturing technology and verified prototypes. These technologies will be demonstrated in the domain of Patient Monitoring by two use cases (1) Sepsis and (2) Delirium. New developments in micro-nano technology are required, combined with microfluidics to interface with the person鈥檚 bio-liquids and allow for (semi)continuous measurement for 1 week.